Chinese drug Loberamisal extends stroke treatment window from 6 hours to 2 days

Large-scale clinical trial with nearly 1,000 patients from 32 hospitals delivers 13 per cent leap in recovery over standard care alone

Brain cells start dying within minutes of a clot blocking an artery, leading to facial droop, affected speech and in severe cases, paralysis or death. Emergency treatments, such as clot-busting drugs or surgery, must be given within a maximum of six hours.

According to a study published by the top-tier Journal of the American Medical Association on September 10, clinical trials of the drug Loberamisal found it was possible to expand the time available to 48 hours.

The large-scale multicentre phase 3 trial found that 70 per cent of patients who received Loberamisal intravenously within two days of a stroke regained complete functional independence – a leap of 13 percentage points over standard care alone.